de

Novel alloys to reduce inflammatory processes and biofilm formation on implants

Bild von Novel alloys to reduce inflammatory processes and biofilm formation on implants

Novel alloys to reduce inflammatory processes and biofilm formation on implants

Project Lead and Supervision: Prof. Dr. Manja Krüger
Co-Supervision: Prof. Dr. Jessica Bertrand
Project Handling: M.Sc. Rebecca Höpfer

The aim is to develop novel materials for "intelligent implants" that have the potential to minimize or suppress inflammatory processes due to their chemical composition and/or grading. With a view to co-evolution, a reservoir of antibacterial elements is to be incorporated on or below the surface so that they become effective during material degradation (damage due to corrosion, tribology). The sub-project combines material expertise (alloy design, microstructural investigations and mechanical tests) with experimental methods for the quantitative determination of biocompatibility.

 

Bild von Manja Krüger

Prof. Dr. Manja Krüger

Bild von Rebecca Höpfer

M.Sc. Rebecca Höpfer

Peer reviewed articles:

 

Von Heckel C, Walles H, Hasemann G, Krüger M

Modular Ti-6Al-4V system for in vitro optimization of implant materials. Frontiers in Bioengineering and Biotechnology, 13, 2025 https://doi.org/10.3389/fbioe.2025.1661278

 

Conference contributions:

 

Höpfer R, Winter F, Krüger M, Bertrand J

Investigation of the powder metallurgical processability of a novel biomedical Ti-Nb-Ta multicomponent alloy manufactured by mechanical alloying  [Poster presentation] 2025 34th annual Conference of the European Society for Biometerials (ESB). Torino, Italy, September 7-11, 2025

 

The full list of TACTIC publications can be found  here

Prof. Krüger's entry in Forschungsportal (LSA) is linked here

Last Modification: 28.07.2026 -
Contact Person: