Novel alloys to reduce inflammatory processes and biofilm formation on implants
Novel alloys to reduce inflammatory processes and biofilm formation on implants
Co-Supervision: Prof. Dr. Jessica Bertrand
Project Handling: M.Sc. Rebecca Höpfer
The aim is to develop novel materials for "intelligent implants" that have the potential to minimize or suppress inflammatory processes due to their chemical composition and/or grading. With a view to co-evolution, a reservoir of antibacterial elements is to be incorporated on or below the surface so that they become effective during material degradation (damage due to corrosion, tribology). The sub-project combines material expertise (alloy design, microstructural investigations and mechanical tests) with experimental methods for the quantitative determination of biocompatibility.
Peer reviewed articles:
Von Heckel C, Walles H, Hasemann G, Krüger M
Modular Ti-6Al-4V system for in vitro optimization of implant materials. Frontiers in Bioengineering and Biotechnology, 13, 2025 https://doi.org/10.3389/fbioe.2025.1661278
Conference contributions:
Höpfer R, Winter F, Krüger M, Bertrand J
Investigation of the powder metallurgical processability of a novel biomedical Ti-Nb-Ta multicomponent alloy manufactured by mechanical alloying [Poster presentation] 2025 34th annual Conference of the European Society for Biometerials (ESB). Torino, Italy, September 7-11, 2025
The full list of TACTIC publications can be found here
Prof. Krüger's entry in Forschungsportal (LSA) is linked here